Radhakrishnan P. Iyer

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Antiviral Efficacy and Host Immune Response Induction during Sequential Treatment with SB 9200 Followed by Entecavir in Woodchucks

Jan 05, 2017 |

By Manasa Suresh, Kyle E. Korolowicz, Maria Balarezo, Radhakrishnan P. Iyer

| PLOS

SB 9200, an orally bioavailable dinucleotide, activates the viral sensor proteins, retinoic acid-inducible gene 1 (RIG-I) and nucleotide-binding oligomerization domain-containing protein 2 (NOD2) causing the induction of the interferon (IFN) signaling cascade for antiviral defense.

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Radhakrishnan P. Iyer

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Antiviral Efficacy and Host Immune Response Induction during Sequential Treatment with SB 9200 Followed by Entecavir in Woodchucks

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