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Raegan M. Weil on Muck Rack

Raegan M. Weil

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Surface-engineered dual drug-loaded tumor-targeted liposomal nanoparticles to overcome the therapeutic resistance in glioblastoma multiforme

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By Ramcharan Singh Angom, Hari Krishnareddy Rachamala, Vijay Sagar Madamsetty, Paola Suarez-Meade, Tanmay A. Kulkarni, Shamit K. Dutta, Enfeng Wang, Santanu Bhattacharya, Krishnendu Pal, Alfredo Quinones-Hinojosa, Debabrata Mukhopadhyay, Beatriz I. Fernandez-Gil, Raegan M. Weil
| Nature Verified
Abstract Glioblastoma (GBM) is the most common high-grade primary malignant brain tumor, characterized by a notably poor prognosis. Current treatments for GBM have shown limited effectiveness in improving patient survival, highlighting the urgent need for effective therapeutic strategies. Combination therapy offers significant potential in overcoming resistance by targeting multiple signaling pathways; however, it often comes with increased toxicity compared to monotherapy.
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