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Rafał Krzysztoń on Muck Rack

Rafał Krzysztoń

As seen in: Nature, Cell Chemical Biology
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Articles

Synthetic gene circuit evolution: Insights and opportunities at the mid-scale

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By Christopher Helenek, Stony Brook, Rafał Krzysztoń, Julia Petreczky
| Cell Chemical Biology Verified
Summary Directed evolution focuses on optimizing single genetic components for predefined engineering goals by artificial mutagenesis and selection. In contrast, experimental evolution studies the adaptation of entire genomes in serially propagated cell populations, to provide an experimental basis for evolutionary theory.
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Nonmonotone invasion landscape by noise-aware control of metastasis activator levels - Nature Chemical Biology

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By Daniela De Martino, Jose Javier Bravo-Cordero, Yiming Wan, Rafał Krzysztoń, Joshua Azukas
| Nature Verified
Cell culture MDA-MB-231 and HEK293 cells were from the American Type Culture Collection. All engineered versions of HEK293 cells (referred to as 293) were cultured in DMEM media with 10% FBS and 1% penicillin–streptomycin. All engineered versions of MDA-MB-231 cells (referred to as MB231) were grown in RPMI 1640 media with 5% FBS and 1% penicillin–streptomycin.
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