Rafael A. Baraúna

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.

Introduction Yersinia pestis is the pathogenic bacteria that causes plague, a naturally occurring epidemic disease (Mordechai et al., 2019; Yang et al., 2023). Y. pestis has been proven to evolve from its ancestor Yersinia pseudotuberculosis around 7400 years ago with limited genomic polymorphisms (Rascovan et al., 2019; Susat et al., 2021). We performed a systematic analysis of public Y.