Rafael Morales-Barrera
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EMETPRO: a multicentric, international, retrospective analysis evaluating patients with metastatic hormone-sensitive prostate cancer with early progression
Abstract Androgen deprivation therapy (ADT) + androgen receptor pathway inhibitor (ARPI) ± docetaxel represent the standard of care in patients with metastatic hormone-sensitive prostate cancer (mHSPC). However, some patients still have early progression (EP). EMETPRO is a multicentric, retrospective registry of patients with EP mHSPC. Patients with EP mHSPC were defined as patients who had progression ≤6 months under ADT+docetaxel or ADT + ARPI or ≤9 months from ADT monotherapy start.
Rogaratinib Plus Atezolizumab in Cisplatin-Ineligible Patients With FGFR RNA-Overexpressing Urothelial Cancer
Key Points Question Can rogaratinib be safely combined with anti–programmed cell death 1 ligand 1 therapy to improve efficacy for patients with advanced/metastatic urothelial carcinoma harboring FGFR3 messenger RNA overexpression?
Whole-body Magnetic Resonance Imaging as a Treatment Response Biomarker in Castration-resistant Prostate Cancer with Bone Metastases: The iPROMET Clinical Trial
Evaluation of bone metastasis in metastatic prostate cancer (mPC) remains a clinical challenge, as computed tomography and bone scans are unable to capture the response of these metastases to therapy. This is relevant for patient management and drug development, as radiographic response is a common intermediate endpoint in phase 1/2 clinical trials [].
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