Rajashri Namdev Kausdikar

Oxidative stress, arising from an imbalance between reactive oxygen species generation and endogenous antioxidant defence capacity, is a major contributing factor in the pathogenesis of chronic diseases including cardiovascular disorders, diabetes mellitus, cancer, and neurodegenerative conditions.

Myristica malabarica Lam. (Myristicaceae), commonly known as Wild Nutmeg or Malabar Nutmeg, is an endemic medicinal tree of the Western Ghats biodiversity hotspot of India, traditionally employed by tribal communities for the management of diabetes mellitus.

Gymnema sylvestre commonly known as Gurmar or sugar destroyer, is one of the most celebrated antidiabetic medicinal plants in Ayurvedic medicine, with over 2,000 years of documented traditional use in the management of diabetes mellitus. The present investigation was undertaken to carry out a comprehensive pharmacognostic, phytochemical, and antidiabetic evaluation of Gymnema sylvestre leaves procured from an authenticated Indian accession.