Rajna Minic

Introduction Combination and polyvalent vaccines not only provide protection against several different pathogens at the same time but can also increase vaccine protection against pathogens that have closely related pathogenic strains or serotypes. In particular, the use of polyvalent conjugate vaccines for Streptococcus pneumoniae is important due to the organism’s many serotypes, each with a distinct polysaccharide capsule (Hausdorff et al., 2000).

Western life style, and high calorie diet in particular is causing major health problems such as insulin resistance, hepatic steatosis and heart disease in modern age. High fat diet (HFD) induces similar changes in mice, such as increased body weight, hypercholesterolemia and accumulation of triglycerides in the liver. These changes can be ameliorated by the administration of some Lactobacillus species.