Skip To Main Content
Rajpal Sian on Muck Rack

Rajpal Sian

As seen in: Nature
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Rajpal

Contact Rajpal, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

BRD2 impedes iPSC reprogramming by regulating lipid biosynthesis and the matrisome via its ET tail

|
By Ricardo Raúl Cevallos, Ruowen Zhang, Shu Chen, Kejin Hu, Rajpal Sian
| Nature Verified
Abstract Induction of human pluripotent stem cells (hiPSCs) from somatic cells encounters significant barriers that remain poorly understood. Lipids are fundamental cellular molecules with many essential roles. However, the roles of lipids in reprogramming are unknown. Here, we show that BRD2 is a barrier to hiPSC reprogramming by suppressing lipid genes and maintaining the somatic transcriptional program, particularly the somatic matrisome program.
Open in Who Shared Issue with article?
See all 1 articles