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Rajshikhar Gupta on Muck Rack

Rajshikhar Gupta

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Articles

Detecting chromatin state alterations in PBMCs associated with Type 2 Diabetes Mellitus

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By Caroline Uhler, GV Shivashankar, Maryam Moazeni Afarani, Rajshikhar Gupta, Issa Fetian
| Nature Verified
Abstract Type 2 Diabetes Mellitus (T2DM) involves patient-specific immune dysfunction not addressed by current diabetes management methods. Traditional methods to assess functional changes to PBMCs are too costly and time-intensive for routine use. We studied 57 individuals across healthy, prediabetic, and diabetic stages, performing chromatin imaging of live peripheral blood mononuclear cells (PBMCs) using a microfluidic imaging assay.
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