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Ranawaka APM Perera

As seen in: BioRxiv, MedPage Today
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Articles

Comparison of SARS-CoV-2 variants of concern in primary human nasal cultures demonstrates Delta as most cytopathic and Omicron as fastest replicating

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By Nikhila S Tanneti, Anant Patel, Andrew Marques, Ranawaka APM Perera
| BioRxiv
Abstract The SARS-CoV-2 pandemic was marked with emerging viral variants, some of which were designated as variants of concern (VOCs) due to selection and rapid circulation in the human population. Here we elucidate functional features of each VOC linked to variations in replication rate. Patient-derived primary nasal cultures grown at air-liquid-interface (ALI) were used to model upper-respiratory infection and human lung epithelial cell lines used to model lower-respiratory infection.
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Comparison of SARS-CoV-2 variants in primary human nasal cultures indicates Delta as most cytopathic and Omicron as fastest replicating

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By Anant Patel, Andrew Marques, Ranawaka APM Perera, Nikhila S Tanneti
| BioRxiv
Abstract The ongoing SARS-CoV-2 pandemic has been marked with emerging viral variants, some of which were designated as variants of concern (VOCs) due to their selection and rapid circulation in the human population. Here we elucidate functional features of each VOC in patient-derived primary nasal cultures grown at air-liquid-interface (ALI) to model upper-respiratory infection, and human lung epithelial cell lines to model lung infection.
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Eurosurveillance | Middle East respiratory syndrome coronavirus (MERS-CoV) neutralising antibodies in a high-risk human population, Morocco, November 2017 to January 2018

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By Ranawaka APM Perera, Anass Abbad, Latifa Anga, Abdellah Faouzi
| Eurosurveillance
Home Eurosurveillance Volume 24, Issue 48, 28/Nov/2019 Article Research Open Access http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2019.24.48.1900244 Like 0 Access full text Article Middle East respiratory syndrome coronavirus (MERS-CoV) neutralising antibodies in a high-risk human population, Morocco, November 2017 to January 2018 Anass Abbad1,2,7, Ranawaka APM Perera3,7, Latifa Anga1, Abdellah Faouzi1, Nhu Nguyen Tran Minh4, Sk Md Mamunur Rahman Malik4, Nadia Iounes2,...
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