Ranchi Xu on Muck Rack

Ranchi Xu

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Articles

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SPH3127: A Phase I, Randomized, Double-Blind, Placebo-Controlled Trial

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By Reviewer Resources, Shan Jing, Ranchi Xu, Kexu Yang
| Clinical Therapeutics Verified
Highlights • This is a randomized, double-blind, placebo-controlled, phase 1 study. • SPH3127 was safe and well-tolerated. • SPH3127 had strong and sustained suppression of plasma renin activity. Abstract Purpose To evaluate the pharmacokinetics, pharmacodynamics, safety, and tolerability of single- and multiple-dose SPH3127 in healthy individuals. Methods This was a randomized, double-blind, placebo-controlled, Phase I dose-escalation study.
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