Randolph M. Baral
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Analytical performance of feline plasma on current Heska and IDEXX point‐of‐care biochemistry analyzers compared with a commercial laboratory analyzer
1 INTRODUCTION Clinicopathologic measurement results must be reliable for clinical use.
Analytical quality performance goals for symmetric dimethylarginine in cats
Background Symmetric dimethylarginine (SDMA) reflects the glomerular filtration rate (GFR) in people, dogs, and cats. Initial assays used a liquid chromatography‐mass spectroscopy (LC) technique. A veterinary immunoassay has been developed for use in commercial laboratories and point‐of‐care (POC) laboratory equipment. There have been no independent assessments of these assays, and analytical performance goals for SDMA testing have not been defined.
Current and emerging concepts in biological and analytical variation applied in clinical practice
Abstract A single laboratory result actually represents a range of possible values, and a given laboratory result is impacted not just by the presence or absence of disease, but also by biological variation of the measurand in question and analytical variation of the equipment used to make the measurement. Biological variation refers to variability in measurand concentration or activity around a homeostatic set point.
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