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Randy Heiland

As seen in: PLOS, Royal Society of Chemistry, BioRxiv
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Articles

[2406.18371] Building multiscale models with PhysiBoSS, an agent-based modeling tool

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By Randy Heiland, Emmanuel Barillot, Paul Macklin, Andrea Checcoli
| arxiv.org
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PhysiCell analysis for breast cancer metastasis model

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By Randy Heiland, Paul Macklin, Lima Da Rocha
| nanohub.org
Researchers should cite this work as follows: Randy Heiland, Lima Da Rocha, Heber, Paul Macklin (2023), "PhysiCell analysis for breast cancer metastasis model," https://nanohub.org/resources/pc4metastasis. (DOI: 10.21981/28TK-0135). BibTex | EndNote
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Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

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By Jeanette Johnson, Genevieve L. Stein-O'Brien, Max BakerRichard Booth, Randy Heiland
| BioRxiv
Abstract Cells are fundamental units of life, constantly interacting and evolving as dynamical systems. While recent spatial multi-omics can quantitate individual cells' characteristics and regulatory programs, forecasting their evolution ultimately requires mathematical modeling. We develop a conceptual framework--a cell behavior hypothesis grammar--that uses natural language statements (cell rules) to create mathematical models.
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