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Alterations in Cerebrospinal Fluid Density Following Contrast Administration in Patients With Acute Ischemic Stroke
1 Introduction Iodine-based contrast media administered intravenously during computer tomography (CT) scan is not normally detected in the cerebrospinal fluid (CSF), as iodine does not penetrate the intact blood–brain barrier (BBB) [1, 2]. However, acute ischemic stroke (AIS) may lead to increased permeability of the BBB [3]. In AIS leaked iodine may be detected in the brain parenchyma on CT imaging showing parenchymal contrast staining [4-7].
Arterial floating mural thrombi are a characteristic imaging pattern in SARS-CoV-2-related ischemic stroke
Discussion Initial reports on the risk of ischemic stroke in patients with SARS-CoV-2 infection were as high as 5.7% with severe infection [10]. Later studies reported lower estimates of 0.5%-1.6 [2, 11–13], which were still significantly higher when compared to patients hospitalized with other respiratory viruses [14].
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