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Rasia C. Li on Muck Rack

Rasia C. Li

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Articles

A cysteine-based molecular code informs collagen C-propeptide assembly

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By Azade S. Hosseini, Andrew S. DiChiara, Rasia C. Li, Patreece H. Suen
| Nature Verified
We began by aligning collagen C-Pro domains from distantly related species across the animal kingdom to track the appearance of each factor that has been proposed to play a key role in collagen assembly through evolutionary history. Our goal was to identify a conserved factor that emerged near the same point as collagen-I heterotrimers, which likely evolved no later than the last common ancestor of all chordates (see Fig. 2b for a cladogram).
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