Ratchnida Kamwa

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Whole-genome sequencing reveals hidden antimicrobial resistance genes in phenotypically susceptible probiotic candidate lactic acid bacteria

Jun 17, 2026 |

By Yuda Putra Disastra, Thidathip Wongsurawat, Piroon Jenjaroenpun, Nuvee Prapasarakul, David John Hampson, Ratchnida Kamwa

| Nature

Abstract Phenotypic assays commonly used to evaluate probiotic safety may fail to detect clinically relevant antimicrobial resistance (AMR), potentially allowing genetically concerning strains to appear acceptable based on MIC testing alone.

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Whole-genome sequencing reveals hidden antimicrobial resistance genes in phenotypically susceptible probiotic candidate lactic acid bacteria

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