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Ravinarayanan Haribalaganesh on Muck Rack

Ravinarayanan Haribalaganesh

As seen in: MDPI, BioRxiv, Future Medicine
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Articles

Hsa-MiR-483 -3p Regulates the Extracellular Matrix Proteins via TGFbeta2/SMAD4 Signaling in the Glucocorticoid-responsive Human Trabecular Meshwork Cells

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By Ravinarayanan Haribalaganesh, Ramasamy Krishnadas, Colin E. Willoughby, Rajendrababu Sharmila
| BioRxiv
Abstract Purpose: To investigate the role of hsa-miR-483-3p on the regulation of extracellular matrix (ECM) in cultured human trabecular meshwork (HTM) cells with known steroid response.
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Genes | Free Full-Text | Small RNA Sequencing Reveals a Distinct MicroRNA Signature between Glucocorticoid Responder and Glucocorticoid Non-Responder Primary Human Trabecular Meshwork Cells after Dexamethasone Treatment

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By Kandasamy Kathirvel, Xiaochen Fan, Ravinarayanan Haribalaganesh, Devarajan Bharanidharan
| MDPI
2. Materials and Methods 2.1. Human Donor Eyes Post-mortem human cadaveric eyes not suitable for corneal transplantation were obtained from the Rotary Aravind International Eye Bank, Aravind Eye Hospital, Madurai. The study was conducted following approval from the Human Ethics Committee of the Institute. The tissues were handled in accordance with the Declaration of Helsinki.
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Small RNA Sequencing Reveals a Distinct MicroRNA Signature between Glucocorticoid Responder and Glucocorticoid Non-responder Primary Human Trabecular Meshwork Cells after Dexamethasone Treatment

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By Xiaochen Fan, Ravinarayanan Haribalaganesh, Kathirvel Kandasamy, Devarajan Bharanidharan
| BioRxiv
Abstract The present study aimed to understand the role of miRNAs in differential glucocorticoid (GC) responsiveness in human trabecular meshwork (HTM) cells using small RNA sequencing. For this, total RNA was extracted from cultured HTM cells with known GC responsiveness using Human organ-cultured anterior segment (HOCAS) (GC-responder GC-R; n=4) and GC-non-responder (GC-NR; n=4) after treatment with either 100nM dexamethasone (DEX) or ethanol (ETH) for 7 days.
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