Ravinash Krishna Kumar

Abstract Controllable gene circuits that respond to defined inputs are essential tools in synthetic biology. By leveraging regulatory mechanisms at either transcriptional or translational levels, synthetic responsive systems have been engineered to recognize diverse signals, such as small molecules (e.g., tetracycline) or physical stimuli (e.g., light).

This month’s Under the Lens discusses a recent advance in the imaging of anaerobic gut bacteria using nanaerobic growth conditions. References 1. Chia, H. E. et al. Extending fluorescence microscopy into anaerobic environments. Curr. Opin. Chem. Biol. 51, 98–104 (2019). CAS Article Google Scholar 2. Whitaker, W. R. et al. Tunable expression tools enable single-cell strain distinction in the gut microbiome. Cell 169, 538–546 (2017). CAS Article Google Scholar 3. García-Bayona, L. et al.