Rebecca Boland

1 Introduction Traumatic brain injury (TBI) is a major source of injury-related death and disability, affecting more than 20 million individuals every year (1). Medical advances have led to a decline in TBI-related deaths, but this contributes to a growing population of survivors who suffer chronic injury-related consequences that can persist for several years after injury. Many of these chronic issues are perpetuated by neuroinflammation and mediated by microglia (2–4).