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Rebecca Simpson on Muck Rack

Rebecca Simpson

As seen in: BMJ Open, BioRxiv

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Articles

Variation in emergency department attendances and acute hospital admissions for ambulatory emergency care: a retrospective analysis of routinely collected NHS data across England

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By Richard Jacques, Rebecca Simpson, Madina Hasan
| BMJ Open Verified
Discussion In this multi-centre descriptive study of more than 1.5 million ED attendances and 660 000 emergency admissions across English hospitals, we found that conditions listed in the AEC Directory accounted for a substantial proportion of acute care activity. We found that 29.6% of first-time attendances at ED and 40.8% of acute admissions were included in the list of AEC-related conditions.
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Genetic variance in the murine defensin locus modulates glucose homeostasis

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By Stewart WC WC Masson, Rebecca Simpson, Harry B. Cutler, Patrick W Carlos
| BioRxiv
Abstract Insulin resistance is a heritable risk factor for many chronic diseases; however, the molecular drivers remain elusive. In seeking these, we genetically mapped insulin sensitivity in 670 chow-fed Diversity Outbred in Australia (DOz) mice. This revealed a genome-wide significant association with the chromosome 8 defensin locus. By taking a systems genetics approach, we ultimately identified alpha-defensin 26 (Defa26) as the causal gene in this region.
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