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Articles

Efficient unified synthesis of diverse bridged polycyclic scaffolds using a complexity-generating ‘stitching’ annulation approach

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By Scott Rice, Daniel Cox, Redbrick Molecular, Stephen P Marsden
| Royal Society of Chemistry Verified
Efficient unified synthesis of diverse bridged polycyclic scaffolds using a complexity-generating ‘stitching’ annulation approach† Regioselective and stereospecific directed C–H arylation of simple amine substrates, and cyclisation, delivered 30 diverse, three-dimensional scaffolds. The unified approach significantly expanded the range of bridged ring systems that contain both a nitrogen atom and an aromatic ring. You have access to this article Please wait while we load your content...
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