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Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy

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By Hill AJ, McFaline-Figueroa JL, Jackson DL, Regalado SG
| ncbi.nlm.nih.gov
This is a preprint. It has not yet been peer reviewed by a journal. The National Library of Medicine is running a pilot to include preprints that result from research funded by NIH in PMC and PubMed. Display options Abstract Chemical genetic screens are a powerful tool for exploring how cancer cells' response to drugs is shaped by their mutations, yet they lack a molecular view of the contribution of individual genes to the response to exposure.
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