Regitze Pinnerup on Muck Rack

Regitze Pinnerup

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Epinephrine versus saline volume expansion in neonatal resuscitation: a blinded randomized piglet study

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By Ida Rønnov-Jessen, Mette Pedersen, Steffen Ringgaard, Mads Hald Andersen, Hannah Andersen, Kasper J. Kyng, Tine B. Henriksen, Kasper V. Seiersen, Sofie Schaaning, Ted C. K. Andelius, Sarah Stærke-Balling, Jonathan F. Azulay, Henriette S. Høg, Regitze Pinnerup, Esben S. S. Hansen, Lærke H. Hansen
| Nature Verified
Abstract The aim of this study was to compare a normal saline bolus versus epinephrine during resuscitation on mortality and brain injury assessed by magnetic resonance spectroscopy (MRS) in newborn piglets. Thirty-two newborn piglets were subjected to hypoxic cardiac arrest and randomized to resuscitation with epinephrine (0.01 mg/kg, n = 16) or saline bolus (0.9%, 10 mL/kg, n = 16). A sham group received no intravenous treatment (n = 8).
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