Rehan Zafar Paracha

Abstract Soil salinity poses a severe threat to global food security, making the halophytic crop Chenopodium quinoa a vital model for sustainable agriculture. While quinoa is known for its extreme salt tolerance, the molecular mechanisms integrating stress perception with metabolic adaptation remain poorly defined.

PLOS ONE, Sep 2023 Hepatitis C virus is a single-stranded RNA based virus which can cause chronic HCV and hepatocellular carcinoma. HCV genotype 3a has relatively higher rate of fibrosis progression, prevalence of steatosis and incidence of HCC. Despite HCVs variation in genomic sequence, the 5’ untranslated region containing internal ribosome entry site (IRES) is highly conserved among all genotypes. It is responsible for translation and initiation of the viral protein.

Loading metrics Open Access Peer-reviewed Research Article Citation: Ejaz S, Paracha RZ, Ejaz S, Jamal Z (2023) Antibody designing against IIIabc junction (JIIIabc) of HCV IRES through affinity maturation; RNA-Antibody docking and interaction analysis. PLoS ONE 18(9): e0291213.