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Related Disorders

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Articles

National implementation of a digital Parkinson’s disease screening programme in Thailand: reach, adoption, and real-world performance of the CheckPD app

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By Zar Kyi, Related Disorders, Pathum Thani
| link.springer.com
GBD 2021 Demographics Collaborators. Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021. Lancet. 2024;403(10440):1989–2056. Article Google Scholar Albin R, Grotewold N. What is the Parkinson Pandemic? Mov Disord. 2023;38(12):2141–4.
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Editorial: Integrating technology into advanced Parkinson's disease management: from screening and evaluation to treatment and prevention

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By Related Disorders
| Frontiers
Parkinson's disease (PD) is one of the most common neurodegenerative disorders, characterized by various motor and non-motor symptoms that profoundly affect the quality of life of patients (1). With the rise in global PD prevalence due to aging populations and because of the possibility of neuroprotective therapy in the future, there is an urgent need for innovative approaches to improve PD diagnosis and management.
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Evaluation of a Mitochondrial Polygenic Score for Parkinson's Disease Across Ancestries

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By Related Disorders, Chin-Hsien Lin, Kajsa Brolin, Björn-Hergen Laabs
| Wiley Online Library Verified
Pathway-specific polygenic scores (PGS) quantify cumulative genetic risk across multiple loci linked by shared biological mechanisms.1, 2 Mitochondrial dysfunction is one such pathway implicated in Parkinson's disease (PD) pathogenesis.1, 2 Leveraging PD genome-wide association study (GWAS) summary statistics from Nalls et al.2 and mitochondrial function–related SNPs curated by Billingsley et al.,1 we previously developed our own mitochondrial-PGS (MGS) using European ancestry data from the...
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