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Remco Bastiaannet

As seen in: BioRxiv
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Articles

Transport Cocktails for Cancer Therapeutics

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By Omkar Bhatavdekar, Michail Kavousanakis, Remco Bastiaannet, Yannis Kevrekidis
| BioRxiv
Abstract Beyond biological cell heterogeneity, evidenced by different resistances to therapeutics, ''delivery heterogeneity'' crucially limits treatment efficacy for advanced solid tumors: variations in therapeutic drug delivery to different tumor areas (perivascular, perinecrotic) leading to nonuniform drug concentrations/doses and to unsuccessful treatment (cancer cell kill).
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