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Remy E Walk on Muck Rack

Remy E Walk

As seen in: BioRxiv
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Articles

The progression of neurovascular features and chemokine signatures of the intervertebral disc with degeneration

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By Remy E Walk, Kaitlyn Broz, Liufang Jing, Ryan Potter
| BioRxiv
Abstract Inflammatory cytokine production and de novo neurovascularization have been identified in painful, degenerated intervertebral discs (IVDs). However, the temporal trajectories of these key pathoanatomical features, including the cascade of inflammatory chemokines and neo- vessel and neurite infiltration, and their associations with IVD degeneration, remain relatively unknown.
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The progression of infiltrating neurovascular features and chemokine production of the caudal intervertebral disc following injury

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By Remy E Walk, Kaitlyn Broz, Liufang Jing, Ryan Potter
| BioRxiv
Abstract The accessibility of the mouse caudal intervertebral disc (IVD) and its geometric semblance to the human IVD make it an attractive model for assessing IVD-specific responses in vivo. The degenerating caudal IVD recapitulates clinical features of the human condition, including the production of inflammatory chemokines, tissue disorganization, and neo- vessels and neurites.
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Analysis of Infiltrating Immune Cells Following Intervertebral Disc Injury Reveals Recruitment of Gamma-Delta (𝛾𝛿) T cells in Female Mice

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By Sade Williams Clayton, Remy E Walk, Laura Mpofu, Garrett WD Easson
| BioRxiv
Abstract Inadequate repair of injured intervertebral discs (IVD) leads to degeneration and contributes to low back pain. Infiltrating immune cells into damaged musculoskeletal tissues are critical mediators of repair, yet little is known about their identities, roles, and temporal regulation following IVD injury.
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