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Ren Matsubara

As seen in: Nature
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Role of β-adrenergic signaling in the development of Porphyromonas gingivalis lipopolysaccharide-induced cardiac dysfunction in mice

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By Ichiro Matsuo, Kenji Suita, Yoshiki Ohnuki, Misao Ishikawa, Aiko Ito, Mariko Abe, Yasumasa Mototani, Takako Nomura, Yoshio Hayakawa, Daichi Chikazu, Akira Matsuo, Satoshi Okumura, Takao Mitsubayashi, Ren Matsubara, Megumi Nariyama
| Nature Verified
Abstract The aims of the present study were to investigate the changes of cardiac dysfunction induced by Porphyromonas gingivalis lipopolysaccharide (PG-LPS, 0.8 mg/kg/day for a week) in mice, and to elucidate the underlying mechanisms, as well as to evaluate the effect of the non-selective β-blocker propranolol (PPL) on the PG-LPS-induced changes.
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