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Articles by René O
MGMT Gene Silencing and Benefit from Temozolomide in Glioblastoma
Methylation-specific PCR was performed on 307 of 573 glioblastoma specimens (53.6 percent) from patients enrolled at 66 of 85 participating centers (Figure 1); adequate paraffin-embedded tumor tissue was not available from 266 patients. MGMT methylation status could be determined for 206 of the 307 tumors (67.1 percent), or 36.0 percent of the tumors from the overall study population.
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MGMT Gene Silencing and Benefit from Temozolomide in Glioblastoma
1Toni Rose Jue, Kyoko Nozue, Ashleigh J. Lester, Swapna Joshi, Lisette B. W. Schroder, Shane P. Whittaker, Sheri Nixdorf, Robert W. Rapkins, Mustafa Khasraw, Kerrie L. McDonald. . (2017) Veliparib in combination with radiotherapy for the treatment of MGMT unmethylated glioblastoma. Journal of Translational Medicine 15:1. CrossRef 2Yashna Paul, Baisakhi Mondal, Vikas Patil, Kumaravel Somasundaram. . (2017) DNA methylation signatures for 2016 WHO classification subtypes of diffuse gliomas.
Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma
1Or Cohen-Inbar, Zhiyuan Xu, Jason P. Sheehan. (2016) Focused ultrasound-aided immunomodulation in glioblastoma multiforme: a therapeutic concept. Journal of Therapeutic Ultrasound 4 CrossRef 2Claire Legendre, Sylvie Avril, Catherine Guillet, Emmanuel Garcion. (2016) Low oxygen tension reverses antineoplastic effect of iron chelator deferasirox in human glioblastoma cells. BMC Cancer 16 CrossRef 3Asha Balakrishnan, Robert Ledford, Michael Jaglal.
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