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Articles by Renhao Yang
Spatiotemporally-guided defunctionalization of nociceptive nerves with capsaicin enhances structural repair in a murine Achilles tendon rupture model
Abstract Chronic Achilles tendinopathy, a prevalent and debilitating condition, impairs daily function and quality of life. While healthy tendons lack internal nerves, pathological ingrowth of sensory nerve fibers into the tendon is now recognized as a key source of chronic pain. These sprouting nerves act as nociceptors and release pain-associated neuropeptides like Substance P (SP) and Calcitonin Gene-Related Peptide (CGRP), perpetuating pain and neurogenic inflammation.
Molecular Mechanisms of Rotator Cuff Degeneration Identified by Spatial Transcriptomics and Multiplex Immunofluorescence
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. References 1, , , et al., “Rotator Cuff Tears,” Nature Reviews Disease Primers 10, no. 1 (2024): 8, https://doi.org/10.1038/s41572-024-00492-3. 2, , , and , “Management of the Irreparable Rotator Cuff Tear,” Journal of the American Academy of Orthopaedic Surgeons 27, no.
Piezoelectric Biointerfaces for Tendon Regeneration: Mechanisms, Materials, and Therapeutic Strategies
Tendon injuries remain clinically challenging due to slow healing, fibrotic scarring, and limited functional recovery. Recent studies have revealed that native tendons possess intrinsic piezoelectric properties, suggesting that electrical cues play an important role in their regenerative processes. Building on this physiological insight, piezoelectric materials have emerged as promising candidates for self-powered and localized stimulation of tendon healing.
The interaction between local state and village collective in China’s market-oriented land reform: a case study in Pidu, Sichuan
ABSTRACT This paper examines China’s market-oriented reform of rural collective operational construction land (RCOC land), with a focus on the often-overlooked responses of village collectives to land deals. Drawing on fieldwork in Pidu, Sichuan (2017–2021), it analyses how village collectives react to land commodification and interact with the local state.
ICTs and economic performance nexus: meta-analysis evidence from country-specific data - Humanities and Social Sciences Communications
Abstract The study explores the dynamic and complex nexus between ICTs and economic performance by applying a meta-analysis with data from 65 typical studies at the country level. The overwhelmingly significant positive effects of ICTs on economic performance are confirmed through the vote count, funnel plot, precision-effect test, and meta-regression analysis. Additionally, differential influences of ICTs on developed and developing countries are investigated.
Graded Modulation of Inflammation by Metal Ion-Coordinated Peptide-Based Hydrogel Chemical Regulators Promotes Tendon–Bone Junction Regeneration
Biological and Medical Applications of Materials and InterfacesAugust 24, 2024 Renxuan Li Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Department of Orthropedics, Sports Medicine Center, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, P. R.
Synergistic Biofilter Tube for Promoting Scarless Tendon Regeneration
Figures References Support Info Abstract Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 This article references 29 other publications. 1 Nourissat, G.; Berenbaum, F.; Duprez, D. Tendon injury: from biology to tendon repair. Nat. Rev. Rheumatol 2015, 11 (4), 223– 233, DOI: 10.1038/nrrheum.2015.26 1 Tendon injury: from biology to tendon repair Nature reviews. Rheumatology (), 11 (4), 223-33 ISSN:.
Gradient bimetallic ion-based hydrogels for tissue microstructure reconstruction of tendon-to-bone insertion
Abstract Although gradients play an essential role in guiding the function of tissues, achieving synchronous regeneration of gradient tissue injuries remains a challenge. Here, a gradient bimetallic (Cu and Zn) ion–based hydrogel was first constructed via the one-step coordinative crosslinking of sulfhydryl groups with copper and zinc ions for the microstructure reconstruction of the tendon-to-bone insertion.
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