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Pain control with peripheral blood mononuclear cells (PBMC) implantation in Rutherford V/VI patients with ineffective or impossible revascularization. Preliminary results of a multicenter study with PBMC implantation
The need for prompt treatment of Rutherford stage V and VI lesions arises from the frequency of amputations. There are about 120 to 500 amputations per million inhabitants, with an annual increase of 23% over the past decade. Regenerative therapies are used as adjuncts to revascularization or when revascularization fails or as an alternative in patients who are ineligible for surgery or who have severe comorbidities that may contraindicate surgery.
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