Reoto Mio on Muck Rack

Reoto Mio

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A Detection System Using Sensing Motif-tethered Oligodeoxynucleotides for Multiplex Biomolecular Analysis

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By Tatsuya Nishihara, Yuto Motohashi, Reoto Mio, Masato Sugawara
| Royal Society of Chemistry Verified
A Detection System Using Sensing Motif-tethered Oligodeoxynucleotides for Multiplex Biomolecular Analysis We developed a system to detect multiple target biomolecules through sensing motif-tethered oligodeoxynucleotides. DNA-based molecular probes gave the primary amine motif upon reaction with the target biomolecules, gluthione (GSH) and H2O2. After labelling with biotin, the product DNAs were selectively collected to be quantified by qPCR.
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