Resie van Spaendonk on Muck Rack

Resie van Spaendonk

As seen in: Nature
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Resie

Contact Resie, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease - Nature Genetics

|
By Henne Holstege, Marc Hulsman, Rebecca Sims, Shahzad Ahmad, Najaf Amin, Oriol Dols-Icardo, Philippe Amouyel, Claudine Berr, Joshua C. Bis, Stéphanie Debette, Lindsay A Farrer, Maria Fernandez, María Fernández Verified, Nick Fox Verified, Daniela Galimberti, Emmanuelle Génin, Yann Le Guen, Jonathan Haines, M. Arfan Ikram, Robert Kraaij, Merel O. Mol, Kevin Morgan, Adam C. Naj, Valerio Napolioni, Florence Pasquier, Margaret A. Pericak-Vance, Rachel Raybould, Richard Redon, Steffi G. Riedel-Heller, Fernando Rivadeneira, Jonathan M Schott, Sudha Seshadri, Gianfranco Spalletta, André G. Uitterlinden, Jennifer S. Yokoyama, Alfredo Ramirez, Alfredo Ramírez, Simon Mead, Julie Williams, Gaël Nicolas, Céline Bellenguez, Olivier Quenez, Detelina Grozeva, Penny J. Norsworthy, Paola Bossù, J. Nicholas Cochran, Benedetta Nacmias, Pascual Sanchez-Juan, Resie van Spaendonk, Niccolo’ Tesi
| Nature Verified
Abstract Alzheimer’s disease (AD), the leading cause of dementia, has an estimated heritability of approximately 70%1. The genetic component of AD has been mainly assessed using genome-wide association studies, which do not capture the risk contributed by rare variants2. Here, we compared the gene-based burden of rare damaging variants in exome sequencing data from 32,558 individuals—16,036 AD cases and 16,522 controls.
Open in Who Shared Issue with article?
See all 1 articles
 •  Privacy  •  Terms  •  Security and Legal  •   •   •   • 

© 2026 Muck Rack

SOC 2® Certified