Rhea N Caldwell

Progress and limitations in reactive oxygen species quantitation Reactive oxygen species (ROS) are a set of oxygen- and nitrogen-containing radicals. They are produced from a wide range of sources. In biological contexts, cellular stress leads to an overproduction of ROS, which can lead to genetic damage and disease development. In industry, ROS are often productively used for water purification or for analyzing the possible toxicity of an industrial process.

Isobaric 6-plex and tosyl dual tagging for the determination of positional isomers and quantitation of monounsaturated fatty acids using rapid UHPLC-MS/MS MICHAEL ARMBRUSTER, Mahmoud Elhusseiny Mostafa, Scott F. Grady, Rhea N Caldwell, Chris Arnatt and Jim Edwards Abstract Isobaric labelling of fatty acids is complicated by chromatographic co-elution of double bond isomers. This produces contaminated spectra which can mask important biological changes.