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Riccardo Barchiesi on Muck Rack

Riccardo Barchiesi

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Articles

Repeated TLR7 activation induces cell type- and brain region-specific transcriptome changes in male mice

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By Nihal A. Salem, Wen Chen, Marion M Friske, Riccardo Barchiesi, Ruth L Allard, Anna C Dobre, Nicholas Rhyan, R Dayne Mayfield
| Nature Verified
Abstract Alcohol consumption triggers neuroinflammation, potentially creating a feed-forward loop that increases drinking. Previous studies have shown that activation of the toll-like receptor 7 (TLR7) leads to escalated drinking. In this study, we aim to identify cell type-specific transcriptomic patterns underlying TLR7-induced neuroinflammation, potentially leading to escalated drinking.
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