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Richard A. Edden on Muck Rack

Richard A. Edden

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Distinct sensory atypicalities bridge the gap between brain chemistry and motor dysfunction in autism

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By Jason L. He, Helen Powell, Georg Oeltzschner, Deana Crocetti, Ericka Wodka, Jonathan O’Muircheartaigh, Stewart Mostofsky, Mingrun Shi, Oliver Lack, Alyssa Deronda, Richard A. Edden, Nicolaas A. J. Puts
| Nature Verified
Abstract Sensory and motor difficulties are common in autism. Altered excitation-inhibition (E-I) balance is a putative framework for understanding atypical sensory and motor function. We investigated whether sensory differences of autism mediate motor difficulties of autism via differences in E-I balance. 106 children were included in the study (Autism n = 44, Typical development children (TDC) n = 62, age 10.32 ± 1.49).
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