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Riddhi Kirit Pandya on Muck Rack

Riddhi Kirit Pandya

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Differential sperm histone retention in normozoospermic ejaculates of infertile men negatively affects sperm functional competence and embryo quality

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By Ameya Jijo, Aswathi Cheredath, Shubhashree Uppangala, Riddhi Kirit Pandya
| Wiley Online Library Verified
1 INTRODUCTION Classically, the contribution of spermatozoa to embryogenesis was limited to the transfer of paternal DNA1, 2 and centrioles3 and as a signal to start the metabolic activity of the oocytes.4 However, recent literature involving high-throughput technologies indicates that their contribution is much more central than previously thought.5-7 Several reports have demonstrated that the male gamete imparts various epigenetic marks, RNA and protein molecules to the resultant...
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