Rigmor Højland

Methods This prospective cohort study consecutively enrolled patients with clinically suspected IIH at 2 tertiary headache centers in Denmark (Odense University Hospital [OUH] and the Danish Headache Center, Copenhagen University Hospital-Rigshospitalet, Glostrup, from January 2018 to September 2022). Clinical suspicion of IIH was based on objective findings (papilledema, abducens nerve palsy), symptoms (visual disturbances, headache, pulsatile tinnitus), and phenotype (young women with obesity).

The Journal of Headache and Pain, Sep 2023 Treatment for cluster headache is currently based on a trial-and-error approach. The available preventive treatment is unspecific and based on few and small studies not adhering to modern standards.

Cluster headache (CH) is the most common trigemino-autonomic cephalalgia [1]. The recurrent attacks up to 8 times per day are among the most severe pains described by humans, succeeding gun-shot wounds, giving birth and kidney stones [2]. The life-time prevalence is 1,24/1000 [3] and the typical age of onset is 20–40 years [4]. Existing treatments for CH have originally been developed for other medical conditions and are based on empirical data [5,6,7,8].