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Amyloid β-Cholesterol Interplay: Removal of Cholesterol From the Membranes to Catalyze Aggregation and Amyloid Pathology
25-NBD 25-[N-[(7-nitro-2-1 3-benzoxadiazol-4-yl)methyl]amino]-27-norcholesterol AD Alzheimer's disease AFM atomic force microscopy Aβ42 amyloid beta-protein 42 DMSO dimethyl sulfoxide HFIP hexafluoroisopropanol MD molecular dynamics MβCD methyl-beta cyclodextrin POPC 1-palmitoyl-2-oleoyl-glycero-3-phosphocholine POPS 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine RMS root-mean-square SLB supported lipid bilayer 1 Introduction The age-related formation and accumulation of Amyloid beta (Aβ)...
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