Rita Pinto Proença

Unusual presentation of more common disease/injury Ocular ischaemia due to a spontaneous carotid artery dissection Sara Frazão1, Catarina Perry da Câmara2,3, Rita Pinto Proença4 and Joana Tavares Ferreira3,4 1 Ophthalmology, Instituto de Oftalmologia Doutor Gama Pinto, Lisboa, Portugal 2 Neuroradiology, Centro Hospitalar de Lisboa Central EPE, Lisboa, Portugal 3 Nova Medical School/Faculdade de Ciências Médicas da Universidade Nova de Lisboa, Lisbon, Portugal 4 Ophthalmology, Centro...

Findings that shed new light on the possible pathogenesis of a disease or an adverse effect Late-onset Leber’s hereditary optic neuropathy: the role of environmental factors in hereditary diseases Nuno Moura-Coelho1,2, Rita Pinto Proença1, Joana Tavares Ferreira1,2 and João Paulo Cunha1,2 1 Ophthalmology, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal 2 NOVA Medical School | Faculdade de Ciências Médicas - Universidade Nova de Lisboa (NMS|FCM-UNL), Lisbon, Portugal...

The authors report a case of an orbital metastasis from an occult breast carcinoma. A 66-year-old woman presented with a growing left orbital tumour. Orbital CT scan was consistent with lymphoma. However, ocular pathology revealed small neoplastic cells showing an ‘indian file pattern’ suggestive of metastatic carcinoma and immunohistochemistry was positive for CK7, CK CAM5.2 and oestrogen receptor. A systemic evaluation was then performed with mammogram, breast ultrasound and MRI considered normal.