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Image analysis method for measurement and prediction of intra‐matrix IgG diffusion
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description btpr70085-sup-0001-Supinfo.docxWord 2007 document , 1.8 MB Data S1: Supplementary Information. btpr70085-sup-0002-Video.mp4MPEG-4 video, 185.4 MB Video S1: Procedure for image analysis: step-by-step explanation and example. REFERENCES 1.
Hyaluronic Acid Matrices for In Situ Measurement of Protein Diffusion Coefficients
ECM extracellular matrix HA hyaluronic acid ISM in vitro Subcutaneous Matrix SEC size exclusion chromatography SQ subcutaneous 1 Introduction Monoclonal antibodies (mAbs) constitute two-thirds of current biopharmaceutical protein products with nearly 1200 antibodies at various stages of testing, worldwide, as of November 2022 [1]. In the United States, there are 122 mAbs approved by the Food and Drug Administration (FDA) as of June 2022 [2].
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