Riyaz Patel on Muck Rack

Riyaz Patel

London
As seen in: BMJ Open, MSN South Africa, The Telegraph, Wiley Clinical Healthcare Hub, heart, Cooking the Books with Frances Cook, CGTN, The South African, Tiger Sniff, The European Heart Journal Podcast
Public Diplomacy & Communications. RP’s and links are NOT endorsements and DO NOT IN ANY WAY reflect the views of the Embassy of Ireland - South Africa
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Articles

VERVE-102单次基因编辑降脂疗效持续18个月，最大降幅62%

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By Riyaz Patel
| Tiger Sniff
降血脂，正在逐步进入“单次治疗时代”。 5月25日，《新英格兰医学杂志》发布“终身降脂”疗法VERVE-102的I期临床数据，仅单次静脉输注，就有效改善了低密度脂蛋白胆固醇（LDL-C）水平，最大降幅达62%，疗效持续至少18个月。 VERVE-102是一种基因编辑疗法，由于它能够直接关闭引起高脂血症的关键基因，理论上能实现“一针管终身”的降脂效果。 有专家评论称，这意味着基因工程疗法，在治疗慢性疾病中迈出了临床应用的重要一步，具有医学史意义。 英国伦敦大学学院心脏病学教授Riyaz S.Patel分析道，临床上，有一部分患者尝试了一切方法，血脂仍不达标，罹患心血管疾病的风险极高。而新疗法或从基因层面，为患者提供终生保护，将极大改变降血脂的基本逻辑。 LDL-C最大降幅超60% 相关统计数据显示，目前，我国的心血管病人数达到3.3亿，每年约458万人死于心血管病，占全民死因构成的40%以上。其中，动脉粥样硬化性心血管疾病（ASCVD），包括脑卒中、冠心病、心肌梗死等是主要的致死因素。...
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Will you take the opportunity to assess and manage cardiovascular risk?

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By Riyaz Patel, Roth GA, Mensah GA, Johnson Co
| Wiley Clinical Healthcare Hub
Cardiovascular disease (CVD) is the leading cause of premature mortality worldwide.1 In developed nations, progress in reducing CVD mortality has plateaued while low- and middle-income countries are seeing increases in association with greater urbanisation and higher global incidence of diabetes and obesity.2, 3 A greater share of this burden of premature CVD is experienced by men, who consistently have a higher incidence and prevalence of CVD compared with women at all ages in almost all...
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Going green in cardiology

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By Glen Road, West Smithfield, Riyaz Patel
| The European Heart Journal Podcast
As the global population expands and the effects of climate change on health and disease become more pronounced, there is an urgent need to rethink our connection to the environment. Observations of unprecedented weather patterns and extensive climate research underscore this urgency. Consequently, every sector of society, including healthcare, must reassess and recalibrate its environmental footprint.
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