Robert Barker
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Metabolic cost of external work: a novel CPET parameter optimises characterisation of exercise performance in obese individuals - European Journal of Applied Physiology
Abstract Both obesity and cardiorespiratory fitness are crucial determinants of symptoms and prognosis. However, interpreting the gold-standard cardiopulmonary exercise test (CPET) is complicated by increasing body size and varying body composition. We hypothesised that the ‘metabolic cost of external work’ (or oxygen uptake (ml/min)/workload (Watts); V̇O2/W), a body weight-independent determinant of endurance capacity, would reflect metabolic health more accurately than V̇O2 alone.
Hydration Forces Dominate Surface Charge Dependent Lipid Bilayer Interactions under Physiological Conditions
Cell membranes are naturally surrounded by physiological salt solution (150–300 mM), and the interaction of ions with the lipid bilayer membrane plays a fundamental role in steering biological processes.
Metabolic risk factors and incident advanced liver disease in non-alcoholic fatty liver disease (NAFLD): A systematic review and meta-analysis of population-based observational studies
Loading metrics Open Access Peer-reviewed Research Article Helen Jarvis , Dawn Craig, Robert Barker, Gemma Spiers, Daniel Stow, Quentin M. Anstee , Barbara Hanratty Helen Jarvis, Dawn Craig, Robert Barker, Gemma Spiers, Daniel Stow, Quentin M. Anstee, Barbara Hanratty Published: April 30, 2020 https://doi.org/10.1371/journal.pmed.1003100 Figures Abstract Background Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease worldwide.
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