Robert J. Benschop

Supporting Information Filename Description art42856-sup-0001-Disclosureform.pdfPDF document, 385.1 KB Disclosure Form art42856-sup-0002-FigureS2.tifTIFF image, 2.7 MB Supplementary Figure 1. Effect of inflammatory cytokines on NUB1 induction in FLS. (A) mRNA expression of NUB1 induction between RA FLS and OA FLS stimulated with IL-1β (0, 0.0002, 0.002 or 0.02 ng/ml, 6 hours, OA: n=3, RA: n=3).

Microglia modulates PD risk Previous studies have identified variants in the LRRK2 gene that are associated with an increased risk of developing Parkinson’s disease (PD). Here, Langston and colleagues studied the mechanisms of LRRK2 variants to PD and showed that the disease risk is determined by microglial cells.

Information Published In Science Translational Medicine Volume 14 | Issue 654 July 2022 Copyright Copyright © 2022 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. This is an article distributed under the terms of the Science Journals Default License. Submission history Received: 2 December 2021 Accepted: 1 July 2022 Permissions Request permissions for this article.