The restoration of fire-damaged historical monuments entails a wide range of scientific questions. Taking as a starting point the case of Notre-Dame de Paris, this Comment defines the materials science challenges of post-fire restoration, and also briefly outlines the issues of structural integrity, fire safety and preservation ethics. Fig. 1: Notre-Dame de Paris, 22 July 2019. Patrick Zachmann/Magnum Photos/Keystone Fig. 2: Notre-Dame de Paris, 25 June 2019.