Robert Lisak
Joliet
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Articles by Robert Lisak
Use of Therapeutic Plasma Exchange in Autoimmune Neuromuscular Disorders
The objectives of this activity are to: (1) Describe the indications, mechanisms of action, and clinical rationale for therapeutic plasma exchange (TPE) in autoimmune neuromuscular disorders. (2) Evaluate current evidence and practice guidelines from the American Academy of Neurology and the American Society for Apheresis (ASFA) to guide appropriate TPE use.
Yale School of Medicine Receives $27.7 Million Grant Toward Autism Research
Led by Murat G√ľnel, MD, the interdisciplinary research project aims to leverage state-of-the-art technologies and cross-departmental expertise to develop large brain models that will serve as the basis for personalized, circuit-based therapies. Credit: Robert Lisak/Yale School of Medicine
Yale School of Medicine Receives $27.7 Million Grant Toward Autism Research
Led by Murat Günel, MD, the interdisciplinary research project aims to leverage state-of-the-art technologies and cross-departmental expertise to develop large brain models that will serve as the basis for personalized, circuit-based therapies. Credit: Robert Lisak/Yale School of Medicine
This Week in New Haven (October 7 - 13)
Public park parties, abstract art affairs and many more moments begin with a tribute to the ultimate man of letters. Monday, October 7 Ahead of National Dictionary Day—which is timed for foundational lexicographer (and New Havener) Noah Webster’s birthday on October 16—the next virtual Mondays at Beinecke talk, starting at 4:30 p.m., features “highlights from the library’s extensive collections related to Noah Webster [and] his life, family, and work.” Also, New Haven Restaurant Week is underway.
Recurrent Optic Neuritis and Perineuritis Followed by an Unexpected Discovery
Inflammatory and Infectious Considerations ON in multiple sclerosis is typically unilateral with mild to moderate vision loss with diffuse or central visual field loss (Table).3 Ophthalmoscopy is typically unremarkable acutely (given the retrobulbar localization of the initial lesion in most), and MRI might demonstrate unilateral, retrobulbar, and/or canalicular short anterior segment lesions with optic nerve enhancement acutely in most (Table).4 NMOSD and MOG antibody disease (MOGAD) ON...
Encephalitis and Myelitis in a Young Woman
Case Presentation A 31-year-old woman presented with fever, ataxia, double vision, confusion, and auditory hallucinations, preceded by 2 weeks of cough, increased oral secretions, and dermatomal rash. Her medical history was unremarkable. Her family history was notable for first-degree relatives with autoimmune disorders, including Crohn disease and immune thrombocytopenic purpura. On initial examination, she was intubated, febrile (≥38.5°C), and comatose.
Treating MS after surviving PML: Discrete strategies for rescue, remission, and recovery patient 1
Case presentation A 38-year-old woman with MS receiving natalizumab presented to the neurology clinic with the complaint of a new neurologic symptom. Clinical course The patient had a 6-year history of clinically stable MS, albeit exhibiting radiographic progression despite strict adherence to daily subcutaneous glatiramer acetate (GA).
Thymectomy and myasthenia gravis
Myasthenia gravis (MG) is a disorder of the neuromuscular junction mediated by the actions of autoantibodies directed against one of several proteins expressed on the postjunction muscle membrane. For the large majority of MG patients the target for the autoantibodies is the acetylcholine receptor (AChR) (1) that interacts with acetylcholine, the transmitter released by the motor nerve, to trigger muscle contraction.
A young man with numbness in arms and legs
Case presentation A gentleman in his late 40s developed a “pins and needles” sensation and numbness in his left hand that was exacerbated by leaning on his left arm or hyperextending his neck. The numbness developed over a few weeks. Over the next 2 months, the numbness spread proximally in the left arm, then to the right arm, and in patches over his bilateral upper chest and next to the bilateral posterior thighs.
Progress over 100 years
An in-depth look at progress on gender equality at YSM over the last century. If Louise Farnam, PhD ’16, MD ’20, one of Yale’s first women medical students admitted, were to stroll past Sterling Hall of Medicine today, she might be struck by the number of female students, faculty, and administrators on campus. Just over a century ago, Yale School of Medicine wasn’t training women to become physicians.
Investors see silver lining in energy sector
Investors are stepping back into energy, but this time they are looking to capitalize on the industry's distress. This year alone, the $104 billion Washington State Investment Board, Olympia; $29.1 billion Indiana Public Retirement System, Indianapolis; and $20 billion San Francisco City & County Employees' Retirement System have all invested in energy. Energy has been a thrill ride for investors, reaching amazing heights only to crash as little as a year later.
In Memoriam: John F. Kurtzke, MD (1926-2015): A Founding Father of Neuroepidemiology and Pioneer of Modern Clinical Trial Design
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
West Bank mosque attacked; mayor blames settlers
RAMALLAH, West Bank (AP) — A Palestinian official says an attack against a mosque in the West Bank ignited a fire that destroyed its first floor.
Swede wins World Series of Poker, $10 million
LAS VEGAS (AP) — The Swedish man who got his start playing online poker after late restaurant nights while he trained to be a chef is $10 million richer after winning the top World Series of Poker main event prize Tuesday night. Martin Jacobson, 27, had three tens to beat Felix Stephensen of Norway and his pair of nines.
Tuesday's high school results
results Field hockey Class L semifinals Glastonbury 1, Cheshire 0 Darien 1, New Milford 0 Class M semifinals Wilton 2, Lauralton Hall 1 Hand 2, Avon 1 Class S semifinals at Wethersfield Lewis Mills 2, Killingly 0 Granby Memorial 2, Stonington 1 (OT) Boys soccer Class LL semifinals Glastonbury 3, Darien 0 Class L semifinals Branford 1, Barlow 0 Class S semifinals Somers 2, Cromwell 1 (PK 4-2) East Hampton 2, Haddam-Killingworth 1 (PK 4-2) Girls soccer Class LL semifinals Warde 1, Ridgefield 0...
Arctic storm has Colorado shoveling ... tumbleweed
PUEBLO, Colo. (AP) — An arctic storm system has some Coloradoans shoveling out from under tumbleweeds rather than snow. Tumbleweeds piled up around houses and shops and along roads several feet high in and around Colorado Springs and Pueblo on Monday as the system moved from north to south across the state. Peggy Perales of the National Weather Service in Pueblo, Colorado says winds gusted up to 60 mph as the storm moved in.
Wounded Iraq War veteran, anti-war activist dies
SEATTLE (AP) — Tomas Young, a wounded Iraq War veteran who was an outspoken critic of the conflict and the subject of the 2007 documentary "Body of War," has died. He was 34. Young died early Monday at his home in Seattle, his wife, Claudia Cuellar, told The Associated Press on Tuesday. "He just went to sleep and never came back," she said. Details about the cause of death were pending, the King County medical examiner's office said.
Gun pointed during argument over Battleship game
SALT LAKE CITY (AP) — A Utah man is accused of threatening his teenage daughter with a rifle during an argument that began over a game of Battleship. Police say the 68-year-old man was with his 17-year-old daughter in a rural area when he accused her of cheating and broke the game. Utah County authorities say the girl tried to leave the trailer where they were playing, but the man dragged her back by her hair and pointed the loaded rifle at her head.
Stamford Almanac 11.12
EPILEPSY SUPPORT GROUP The Epilepsy Foundation of Connecticut offers a Stamford support group on the second Thursday of every month from 7 to 8:30 p.m. Group meets at the Stamford Government Center in the seminar room on the second floor. All are welcome and there is free parking. For more information, call 800-899-3745. CANCER SUPPORT GROUP Meets Thursdays at 11 a.m. at the Unitarian Universalist Society in Stamford, 20 Forest St., across from the Avon Theater.
Police briefs - StamfordAdvocate
STAMFORD -- Police say a 53-year-old Stamford woman was attacked from behind on a heavily traveled downtown street early Monday evening and had her purse snatched. The woman was walking by 700 Summer St. when a man came up from behind and punched her in the back. The woman held on to her purse while the man tried to wrench it out of her grasp and ended up throwing her to the ground, Lt. Diedrich Hohn said.
Thumbs up, thumbs down
Thumbs up to the first Greenwich Restaurant Week, which launches Thursday, Nov. 13, and will run through Nov. 19. The traditional Stamford Restaurant Week offers set prices, while the bargains in Greenwich are mostly a la carte. Organizers are hoping to help foodies navigate the offerings through a mobile app that is available at no cost in the Apple App Store.
Man rescued from Colorado department store's walls
LONGMONT, Colo. (AP) — Authorities say a man who was freed from a space between two walls of a Colorado department store may have been there for several days yelling for help. Longmont police Sgt. Matt Cage says Paul Felyk was rescued Tuesday. The Longmont Times-Call reports (http://tinyurl.com/mokop25 ) firefighters used a circular saw to cut into the side of the building to free him. Employees at the Marshalls store reported hearing someone yelling Monday but couldn't tell where it was coming from.
Former Ravens cheerleader officially divorced
BALTIMORE (AP) — A former Baltimore Ravens cheerleader who has been charged with raping one teenage boy and providing others with alcohol is officially divorced from her estranged husband, a prominent Maryland energy executive. A Baltimore County judge signed Mayo and Molly Shattuck's divorce order on Nov. 3, the same day a grand jury indicted Molly Shattuck on charges of third-degree rape, unlawful sexual contact and providing alcohol to minors.
Whoopi Goldberg writing book about marriage
NEW YORK (AP) — After three husbands, Whoopi Goldberg is not about to become a wedding planner. The Oscar-winning actress and moderator for "The View" has a deal with Hachette Books for a "provocative" take on the "downsides" of marriage, the publisher announced Tuesday. The book, currently untitled, is scheduled to come out next September. Goldberg, who turns 59 this week, had brief marriages to Alvin Martin, David Claessen and Lyle Trachtenberg.
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