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A Phase 2 Trial to Test Safety and Efficacy of ST-100, a Unique Collagen Mimetic Peptide Ophthalmic Solution for Dry Eye Disease
Abstract Dry eye disease (DED) is a worldwide source of ocular discomfort. This first-in-human Phase 2 multi-center clinical study determined safety and efficacy of treating signs and symptoms of DED using an ophthalmic solution containing a synthesized mimetic of human collagen (ST-100). This double-masked, randomized, study compared the effects of high (60 μg/ml) and low (22 μg/ml) dose ST-100 to vehicle utilizing the Ora, Inc.
Collagen Mimetic Peptides Promote Repair of MMP-1-Damaged Collagen in the Rodent Sclera and Optic Nerve Head
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