Robert Wiener

Abstract Fibromuscular dysplasia (FMD) is a poorly understood disease affecting 3–5% of adult females. The pathobiology of FMD involves arterial lesions of stenosis, dissection, tortuosity, dilation and aneurysm, which can lead to hypertension, stroke, myocardial infarction and even death. Currently, there are no animal models for FMD and few insights as to its pathobiology.

Abstract Marfan Syndrome (MFS), a connective tissue disorder caused by a mutation in the fibrillin-1 gene, occurs in approximately 1 in 5,000 people worldwide. As an important constituent of the extracellular matrix, mutated fibrillin-1 in Marfan Syndrome leads to aortic medial degeneration, aneurysm, and dissection. TGFβ in the matrix, which is controlled by fibrillin-1, is known to cause pathological effects in smooth muscle cells (SMCs) within the aortic wall during MFS.

After foray into clergy-sharing, Inna Serebro-Litvak is religious leader at Reform temple in Succasunna It was not always easy for Inna Serebro-Litvak as she sought to fulfill her dream of getting a Jewish education in her hometown of St. Petersburg, Russia. But some 40 years later, she is what she long aspired to be — a rabbi and a cantor. On July 1, she became the religious leader at Temple Shalom Roxbury Reform in Succasunna.