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Robert Zitterbart on Muck Rack

Robert Zitterbart

As seen in: Royal Society of Chemistry, Chemistry World
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Articles

Traceless parallel peptide purification by a first-in-class reductively cleavable linker system featuring a safety-release

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By Robert Zitterbart, Nadja Berger, Oliver Reimann, Gavin Noble
| Royal Society of Chemistry Verified
Traceless parallel peptide purification by a first-in-class reductively cleavable linker system featuring a safety-release† Robert Zitterbart, ‡*a Nadja Berger, ‡a Oliver Reimann, a Gavin T. Noble, b Stephan Lüdtke,a Dominik Sarma‡a and Oliver Seitz c Abstract Hundreds of peptides can be synthesized by automated parallel synthesizers in a single run.
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Total chemical synthesis of proteins without HPLC purification

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By Oliver Seitz, Simon F Loibl, Robert Zitterbart
| Chemistry World Verified
The total chemical synthesis of proteins is a tedious and time-consuming endavour. The typical steps involve solid phase synthesis of peptide thioesters and cysteinyl peptides, native chemical ligation (NCL) in solution, desulfurization or removal of ligation auxiliaries in case of extended NCL as well as many intermediary and final HPLC purification steps.
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