Robin John Dart

Researchers have shown how the presence of Vg4 T cells can reduce the risk of inflammatory bowel disease (IBD) relapse, which could not only be a new therapeutic avenue for IBD but also explain its link with colon cancer. Researchers at King’s, the Francis Crick Institute, and Guy’s & St Thomas NHS Foundation Trust have characterised a specialised type of immune cell, which plays a key role in protecting and repairing the cells in the healthy human gut.

Introduction A 30-year-old woman with long-standing irritable bowel syndrome presented to the emergency department with syncope, on a background of 3 weeks of bloody diarrhoea and 6 kg weight loss. She did not smoke, took only the combined oral contraceptive and reported no recent travel. Laboratory tests revealed a macrocytic anaemia: Hb 48 g/L mean corpuscular volume 100.8 fL and reticulocytes 115.2 109 /L.

http://orcid.org/0000-0003-3470-8210Robin John Dart1,2, Mallika Sekhar3, Katie Planche4, Martyn Caplin2, Charles Murray2 1 Peter Gorer Department of Immunobiology, King's College London, London, UK 2 Gastroenterology and Hepatobiliary Medicine, Royal Free London NHS Foundation Trust, London, UK 3 Haematology, Royal Free Hospital, London, UK 4 Radiology, Royal Free Hospital, London, UK Correspondence to Dr Robin John Dart, Peter Gorer Department of Immunobiology, King's College London, London,...